Summary

The Esophageal Cancer Clinical Data Interactive Analysis (ECCDIA)

ECCDIA: an interactive web tool for comprehensive clinical and survival data analysis of esophageal cancer (r version). The Esophageal Cancer Clinical Data Interactive Analysis (ECCDIA, <http://webapps.3steps.cn/ECCDIA/>) was developed to provide basic data analysis, survival analysis, and nomogram of the overall group and subgroup of 77,273 EC patients. The basic data analysis contained clinical factor ratio distribution analysis, Sankey plot analysis for relationships between clinical factors, and a map of clinical factors’ distribution. The survival analysis included Kaplan-Meier (K-M) analysis and Cox analysis for different subgroups of EC patients. The nomogram module enabled clinicians to precisely predict different subgroups of EC patients’ survival probability.


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Data Map

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Map

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Clinical Parameter Ratio



Frequency Distribution

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Frequency Distribution

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Survival Rate

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Survival Rate Table

Static Survival Analysis

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Dynamic Survival Analysis

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Output

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Nomogram

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Train

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Test

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All

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ECCDIA

ECCDIA Description

ECCDIA: an interactive web tool for comprehensive clinical and survival data analysis of esophageal cancer (r version). The Esophageal Cancer Clinical Data Interactive Analysis (ECCDIA, http://webapps.3steps.cn/ECCDIA/) was developed to provide basic data analysis, survival analysis, and nomogram of the overall group and subgroup of 77,273 EC patients. The basic data analysis contained clinical factor ratio distribution analysis, Sankey plot analysis for relationships between clinical factors, and a map of clinical factors’ distribution. The survival analysis included Kaplan-Meier (K-M) analysis and Cox analysis for different subgroups of EC patients. The nomogram module enabled clinicians to precisely predict different subgroups of EC patients’ survival probability.

Abberation Table

Clinical Factor (Raw Name) Clinical Factor (Raw) Clinical Factor (Redefined) Clinical Factor (Redefine Name)
Sex Male Male Sex
Female Female
Primary Site C15.0-Cervical esophagus CE Primary_Site
C15.1-Thoracic esophagus TE
C15.2-Abdominal esophagus AE
C15.3-Upper third of esophagus UTE
C15.4-Middle third of esophagus MTE
C15.5-Lower third of esophagus LTE
C15.8-Overlapping lesion of esophagus OLE
C15.9-Esophagus, NOS NOS_E
Grade Well differentiated; Grade I I
Moderately differentiated; Grade II II
Poorly differentiated; Grade III III
Undifferentiated; anaplastic; Grade IV IV
Unknown Unknown
Histologic type 8050-8089: squamous cell neoplasms SCC Histologic_type
8140-8389: adenomas and adenocarcinomas AD
Stage 7th IA IA Stage_9_group
IB IB
IIA IIA
IIB IIB
IIIA IIIA
IIIB IIIB
IIIC IIIC
IIINOS IIINOS
IV IV
Unkonwn Unkonwn
Stage 7th IA/B I Stage_4_group
IIA/B II
IIIA/B/C/NOS II
IV IV
Unknown Unknown
T stage 7th T0 T0 T_9_group
T1a T1a
T1b T1b
T1NOS T1NOS
T2 T2
T3 T3
T4a T4a
T4b T4b
T4NOS T4NOS
Tx Tx
T stage 7th T0 T0 T_5_group
T1a/b/NOS T1
T2 T2
T3 T3
T4a/b/NOS T4
Unknown Unknown
N stage 7th N0 N0 N_4_group
N1 N1
N2 N2
N3 N3
NX Unknown
N stage 7th N0 N0 N_2_group
N1/2/3 N1_3
NX Unknown
M stage 7th M0 M0 M
M1 M1
Unknown
Surgery of Primary Site Local tumor destruction LTD Surgery_of_Primary_Site
Local tumor excision LTE
Esophagectomy Esophagectomy
no surgery no_surg
Surgery NOS Unknown
Unknown Unknown
Radiation recode Beam radiation Yes Radiation_recode
Combination of beam with implants or isotopes Yes
Other than beam radiation (1973-1987 cases only) Yes
Radiation, NOS method or source not specified Yes
Radioactive implants (includes brachytherapy) (1988+) Yes
Radioisotopes (1988+) Yes
Recommended, unknown if administered Unknown
Refused (1988+) No
None/Unknown Unknown
Chemotherapy Yes Yes Chemotherapy
No/Unknown No_or_Unknown
Therapy method Surgery (Yes) + Radiation (Yes) + Chemotherapy (Yes) Surg_Rad_Che Therapy_method (based on surgey, radiation and Chemotherapy)
Surgery (Yes) + Radiation (No) + Chemotherapy (Yes) Surg_Che
Surgery (No) + Radiation (Yes) + Chemotherapy (Yes) Rad_Che
Surgery (No) + Radiation (No) + Chemotherapy (Yes) Only_Che
Surgery (Yes) + Radiation (Yes) + Chemotherapy(No_or_Unknown) Almost_Surg_Rad
Surgery (Yes) + Radiation (No) + Chemotherapy(No_or_Unknown) Almost_Only_Surg
Surgery (No) + Radiation (Yes) + Chemotherapy(No_or_Unknown) Almost_Only_Rad
Surgery (No) + Radiation (No) + Chemotherapy(No_or_Unknown) Almost_no_therapy
Unknown Unknown

Author(s)

Jingcheng Yang (yjcyxky@163.com)

Jun Shang (shangjunv@163.com)